Application

Research CategoryStem Cell Research

Detect HESCA-1 (Human Embryonic Stem Cell Antigen-1) using this Anti-HESCA-1 Antibody, clone 051007-4A5 validated for use in IC, IH, IF, FC.

Research Sub CategoryPluripotent & Early Differentiation

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The evolution of our understanding of pluripotent and adult stem cell biology requires specific research tools to permit the characterization, isolation, and expansion of stem cells. HESCA-1, developed in collaboration with Abeome Corporation, is the first in a series of novel, human embyronic stem cell antibodies produced to provide scientists with those needed tools. This novel monoclonal antibody recognizes a newly discovered 200 kDa cell surface protein that has been shown to be expressed in pluripotent human embryonic stem cell (hESC) populations.

Immunogen

BG01v hES cell line

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Liquid in 0.02M PBS, 0.25 NaCl, pH 7.6 with 0.1% Sodium Azide

Specificity

Reactivity to other species has not been determined.

This antibody is positive by immunofluorescence against H1, BG-01, BG01v, and BF02 human embryonic stem (hES) cell lines; however, it is unreactive for differentiated stem cells in teratomas and common feeder lines such as MEF, D-551, and Hs27. Reactivity with other hES lines has not yet been determined.

Storage and Stability

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 1 year from date of receipt.

Target description

200 kDa